The closest alternative to Qwen2.5 72B Instruct is Qwen3.7 Plus — comparable intelligence (53.3 vs —); for a cheaper option, MiniMax M3 runs $0.300/M vs $0.360/M; for more speed, Morph V3 Large hits 2.6k t/s; and the best open-weight substitute is MiniMax M3.
Qwen3.7 Plus is the closest alternative to Qwen2.5 72B Instruct, with an Intelligence Index of 53.3 (Qwen2.5 72B Instruct scores —) at $0.320 per million input tokens.
Yes — MiniMax M3 costs $0.300 per million input tokens versus $0.360 for Qwen2.5 72B Instruct, while staying within ~8 points of its Intelligence Index.
MiniMax M3 is the strongest open-weight alternative to Qwen2.5 72B Instruct — downloadable from Hugging Face and self-hostable, scoring 54.7 on intelligence.