modelgrep

Best LLMs for Science — Mistral

Match · Updated August 2026

The best Mistral model for science is Mistral Medium 3.5, scoring 74.8% on GPQA Diamond — graduate-level physics, chemistry and biology. Mistral Medium 3.1 (58.8%) and Mistral Medium 3 (57.8%) round out the top three.

74.8%GPQA
29.9Intelligence
152 t/sSpeed
$1.50Input /M
262KContext
  1. 1mistralai logo
    mistral-medium-3-5
    ReasoningToolsJSON+129.9 intel · $1.50/M · 152 t/s
    74.8%
    GPQA
  2. 2mistralai logo
    mistral-medium-3.1
    ToolsJSONVision14.7 intel · $0.400/M · 45 t/s
    58.8%
    GPQA
  3. 3mistralai logo
    mistral-medium-3
    ToolsJSONVision12.5 intel · $0.400/M · 41 t/s
    57.8%
    GPQA
  4. 4mistralai logo
    mistral-large-2407
    ToolsJSON7.3 intel · $2.00/M · 131K ctx
    47.2%
    GPQA
  5. 5mistralai logo
    mistral-saba
    ToolsJSON6.4 intel · $0.200/M · 33K ctx
    42.4%
    GPQA
  6. 6mistralai logo
    mistral-large
    ToolsJSON4.4 intel · $2.00/M · 128K ctx
    35.1%
    GPQA
  7. 7mistralai logo
    mixtral-8x22b-instruct
    ToolsJSON4.4 intel · $2.00/M · 66K ctx
    33.2%
    GPQA

How this is ranked

AI models ranked by GPQA Diamond — graduate-level physics, chemistry and biology questions written to be un-Googleable, so the score reflects reasoning from knowledge rather than retrieval. The best large language models for scientific research and hard-science work.

Frequently asked

What is the best Mistral model for science?

The best Mistral model for science is Mistral Medium 3.5, scoring 74.8% on GPQA Diamond — graduate-level physics, chemistry and biology. Mistral Medium 3.1 (58.8%) and Mistral Medium 3 (57.8%) round out the top three.

What's a good alternative to Mistral Medium 3.5?

Mistral Medium 3.1 (58.8%) is the closest alternative on this metric, followed by Mistral Medium 3 (57.8%). See the full ranking above for the tradeoffs.

How many Mistral models are there?

modelgrep tracks 18 Mistral models with live benchmarks, speed, latency and per-provider pricing, led on intelligence by Mistral Medium 3.5. 7 of them qualify for this ranking.

More Mistral rankings

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